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In research models it is studied for its role in neutralising reactive oxygen species (ROS), in immune-cell biology, and in maintaining the redox environment that cells depend on for normal metabolic activity

Shock (2013) 40(6):4925.10.1097/SHK.0000000000000050 37 Valdes-FerrerSIPapoinJDanchoMEOlofssonPLiJLiptonJMet alHMGB1 mediates anemia of inflammation in murine sepsis survivors

Consistent with their inability to suppress toxicity in yeast, mutants SidJ D542/545A and SidJ G719R were less effective in reducing Rab33b ubiquitination induced by SdeA (Figure 2A)

95%, as determined by reducing SDS-PAGE

Kaya I, Jennische E, Lange S, Tarik Baykal A, Malmberg P, Fletcher JS (2020) Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimers disease mice