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It has been shown that while proinflammatory cytokines such as TNF- and IL-1 increase the expression of GR, the formation of the GR/ heterodimer attenuates the function of GR 14 (Figure 1)

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Results from numerous studies have shown significant decreases of PUFAs, in particular, DHA in peripheral blood (plasma and erythrocyte membranes) as well as brain of schizophrenia patients at different developmental phases of the disorder