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Although many authors, and regulators, have highlighted the importance of checking vitamin B 12 levels in patients on metformin and giving replacement therapy (which is easy, cheap and readily available) when appropriate, monitoring is rarely done

Time will also diminish the potency of the vitamins

Long-term management for patients with pernicious anaemia or other permanent causes of malabsorption requires lifelong B12 replacement therapy

To fully understand the article, it is important to understand the procedure to build an ice rink

Therefore, the processes that regulate mitochondrial birth, death, and morphological plasticity are not parallel pathways but are deeply entangled, ensuring that the mitochondrial population remains both abundant and healthy