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We next further investigated whether the observed bell-shaped profile induced by high concentrations of dimeric macrocycles (3,000 nM) or HGF (30 nM) might be due to off-target inhibition of constitutively activated RTKs, which could potentially transactivate Met phosphorylation

Compound over time

It is suggested that you perform the test first thing in the morning after 12 hours of fasting, i.e

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