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Among them, a key focus has been given to curcumin for its anti-cancer, anti-inflammatory, antibacterial, and antioxidant abilities

They showed that the IVD is comprised of 3,100 proteins, encompassing roughly 400 matrisome proteins and 2,700 non-matrisome proteins, with 1,769 proteins detected in three or more profiles

[69] In mice [70] and in rats [71] contextual fear conditioning, within 124 hours, it is associated with altered methylations of several thousand DNA cytosines in genes of hippocampus neurons

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10.1186/s12933-019-0879-0 Summary Keywords mitoepigenetics, mtDNA, ncRNAs, mitochondria, aging, cardiovascular diseases, methylation Citation Mongelli A, Mengozzi A, Geiger M, Gorica E, Mohammed SA, Paneni F, Ruschitzka F and Costantino S (2023) Mitochondrial epigenetics in aging and cardiovascular diseases