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Sensitivity or Allergies to B12 or Its Components: Some individuals may have an allergic reaction to the preservatives or additives in B12 injections, especially those with known sensitivities to certain medications or substances

Vitamin B12 deficiency is treatable, and treatment works best if the problem is diagnosed early

[4] Why Vitamin B12 Can Cause Gastrointestinal Symptoms The mechanisms underlying gastrointestinal side effects from vitamin B12 supplementation are not fully established, but several factors may contribute to stomach discomfort in susceptible individuals

Copper serves as a cofactor for lysyl oxidase and lysyl hydroxylase, enzymes essential for collagen cross-linking and structural integrity

Then, they get regular doses to keep levels right