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Importantly, the upregulation of TGF- expression by 4-HNE in macrophages suggests the presence of a detrimental feedback loop between lipid peroxidation and excessive TGF- production [51]

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It has been reported that the overexpression of DHAR increased grain yield and biomass in transgenic sweet potato, rice, tomato, acerola and tobacco plants 1,2,3,4,5,6,7