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Mitoquinone inhibits these signals, preserving muscle integrity and reducing tenderization

doi: 10.1155/2013/394036 25

In contrast with the mouse and hamster, the rat, guinea pig and man are susceptible to the hepatotoxic effects of AFB 1 [34]

Moreover, the PRDX2MFN2ACSL4 pathway has been implicated in mitochondria-associated ferroptosis and has been suggested to exert protective effects in the diabetic cardiac microvascular system [95].Collectively, these findings highlight that mitochondriallipid crosstalk, coordinated through lipid remodeling programs, represents a key determinant of ferroptotic sensitivity in cardiovascular pathology