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Description

The co-use of kratom and tianeptine, in hindsight, is perhaps unsurprising in that both appear to be used to self-treat anxiety, depression, fatigue, pain, and opioid withdrawal [25, 27, 52, 53]

Methods A total of 24 healthy male Wistar albino rats were separated into 3 groups as REM sleep deprivation group, control sleep deprivation group and control group