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Documented neuroprotection

High-speciofoline and low-speciofoline kratom extracts have similar inhibitory effects on three major CYPs in vitro The cytochromes P450 (CYPs) constitute a superfamily of oxidative enzymes that mediate the metabolism of approximately 50% of the top 200 most prescribed drugs 38

This is why you find it in all sorts of cosmetic actives serums, creams, lotions, ampoules in concentrations appropriate for stability and safety

It is very important to note that these substances of abuse remain prohibited and athletes can still be given sanctions up to four years for presence of a substance of abuse if they cannot establish that its use was out-of-competition and unrelated to sport

Researchers should interpret the rodent amount protocols summarized below as scientific reference for the published model systems, not as guidance for any other context