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Frank S (2010) Tetrabenazine: the first approved drug for the treatment of chorea in US patients with Huntington disease

There's no established tolerable upper intake limit from major health authorities

Moreover, chronic or prolonged supplementation with ALA after the cessation of stress stimuli may not provide additional metabolic or anti-oxidative benefits, and in some cases, may partially associated with histopathological changes in liver or induce pro-oxidant effects under normal physiological conditions (5052)