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Macrophages, in addition to clearing debris, release cytokines and growth factors to coordinate further immune responses and promote tissue repair

Immunopharmacology 39(3):167180 Kraft AD, Johnson DA, Johnson JA (2004) Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult

As we age, cartilage becomes increasingly brittle and easily damaged while bones become more porous

PMC 8609996

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