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The data suggest that iron overload leads to eccentric-hypertrophy remodeling, and amlodipine treatment reversed a significant part of hypertrophic remodeling

Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans

Furthermore, B cells can release immunomodulatory cytokines that are critical for the normal immune system maintenance, and differentiate into effector subsets that secrete polarized cytokines depending on the environment 3

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During times of low energy production, such as under ischemic conditions, metabolic shifts occur from neurons to astrocytes to preserve energy due to the lower energy demand of astrocytes compared to neurons (Deitmer et al., 2019)