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Finally, we explore therapeutic opportunities for targeted metabolic regulators, including traditional Chinese medicine, Sirtuin 1 activators, ATP-Citrate Lyase inhibitors, statins, folic acid, etc., providing new strategies to stabilize plaques and slow the progression of AS

Activity of VT-464, a selective CYP17 lyase inhibitor, in the LNCaP prostate cancer xenograft model [abstract 64]

Second, loss of function or mutation of Axin, GSK-3, and APC as members of the Axin complex can likewise activate the pathway and exert oncogenic effects

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This inside-out approach helps address the root causes of uneven skin tone rather than masking them temporarily