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A clinical study using a combination of melatonin plus low-dose interleukin-2 (IL-2) in 12 patients with advanced cancers of the blood (6 with NHL, 2 with HL) that did not respond to standard therapies found that this therapy prolonged survival

LMNA cDNA was amplified by PCR using the attB-LMNA-F and attB-LMNA-R primers (Table S1), and combined with the pDONR221 vector to generate the middle entry clone (pME- LMNA (WT)) through the BP reaction