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Also, mutations in the SNCA gene, which plays a role in synaptic function and DA transmission, are associated with the formation of Lewy vesicles, impaired mitochondrial function, age-related neurodegeneration, and death of dopaminergic neurons

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Importantly, it does not significantly stimulate ACTH, cortisol, or prolactin release at physiological doses (PMID: 9849822)

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Prince M, Sivanandan R, and Kaczorowski A, et al (2007) Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma Proc Natl Acad Sci 104 973978 PMID: 17210912 PMCID: 1783424 111