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In patients with primary Sjgrens syndrome innate-like MAIT cells display upregulated IL-7R, IFN-, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells

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While this activity has been particularly pronounced in cancer cells in response to the administration of chemotherapy regimens, a variety of other cell types and the administration of other drug classes have been noted (e.g., T-cells and anti-HIV drugs)

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