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10.1016/j.vph.2018.02.010 76 VukojevicJ.VrdoljakB.MalekinusicD.SiroglavicM.MilavicM.KolencD.et al (2020)

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That is, when glutamate binds to the AMPA receptor, the shape of the receptor protein changes, opening a channel for Na + ions

technological (oxidative, cold, high osmotic and high temperature conditions) and physiological stress (oxidative, low pH, high bile salts and toxins)