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One of the most searched oncology questions worldwide is: Is cancer curable? The answer depends on cancer type, stage, and timing of diagnosis

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Contrastingly, in adults, mutations are often identified in just one of the two alleles, hinting at a haploinsufficiency mechanism

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Our present hypothesis is that compounds which can directly target mitochondrial function offer the advantage of mitochondrial-mediated cell death independent of upstream signaling molecules that are impaired in cancer development, treatment and/or drug resistance