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In a clinical study, men with alopecia who applied a GHK-Biotin solution twice daily for four months showed increased follicular activity and a higher percentage of hair in the active growth (anagen) phase compared to those using a placebo (Treb et al., 2007)

But this research shows that, at normal biological levels, small increases in prostaglandin E2 can promote regeneration. A closer investigation of the chondrocytes in the joints of old mice and young mice showed that old chondrocytes expressed more detrimental genes involved in inflammation and the conversion of hyaline cartilage to unwanted bone, and fewer genes involved in cartilage development

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