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doi: 10.1016/j.ccell.2018.04.002 254 TanakaKSasayamaTIrinoYTakataKNagashimaHSatohNet al

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Moreover, smooth-fitting curve analysis identified a threshold effect: below 358.7 pg/mL, each 10 pg/mL increase in vitamin B12 was associated with a 4.4% increase in clinical pregnancy rate (OR = 1.04, P = 0.03), beyond which no further benefit was observed