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PMID: 61 MartyniukCJMartnezRNavarro-MartnLKamstraJHSchwendtAReynaudSet al

The inhalation of NO as a therapeutic strategy for hyperoxic lung injury is still controversial [74]

Pizzorno (2014): Reviewed glutathione as the most important antioxidant in human physiologycritical for detoxification, mitochondrial health, and immune resilience

The resulting ROS can impair DNA, increase lipid peroxidation, lead to arteriosclerosis, destroy the extracellular matrix, stimulate bone erosion, activate osteoclasts, increase inflammation, and finally destroy joints [39]