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Summary MTHFR mutations cause a reduction in or inactivity of the MTHFR enzyme

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This study was performed in accordance with the Guide for the Care and Use of Laboratory Animals published by National Academy of Sciences and with the approval of University Committee for Ethics in Animal Experimentation (protocol # 3401-1)

Caffeine is replaced by vitamin B3, which supports energy metabolism and contributes to the reduction of tiredness and fatigue