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Notably, metabolic inhibition with ketoconazole or CYP51A1 knockdown can reverse this sensitivity, suggesting a context-dependent role for CYP51A1 in treatment resistance [76]

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Briefly, local field potential activity was amplified, A-D converted and sampled at 1 KHz and bandpass filtered at 0.1250 Hz (DigitalLynx SX and Cheetah Data Acquisition System, Neuralynx, USA)