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By targeting senescent cells and modulating mTOR locally, it reduces wrinkles, stimulates collagen, and supports autophagy without systemic exposure

Annals of Oncology, 26, 23752391

PGC-1 rescues Huntingtons disease proteotoxicity by preventing oxidative stress and promoting TFEB function

Funding This work was supported in part by the Ministry of Science and Technology (2016YFA0502303 and 2015CB910300 to LL),the National Natural Science Foundation of China (21633001 to LL), and the Rudolf Virchow Jr

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