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Additionally, the SCD pathway is significant for chemotherapeutic resistance and membrane stability in gliomas [116, 117]

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61 SIRT1 inhibits the activation of the NLRP3 inflammasome, which triggers the production of IL-1, IL-18, and HMGB1, therefore initiating and amplifying the innate immune response

doi: 10.1016/j.eclinm.2021.101213 234 MaRDingXWangYDengYSunA