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Further support was provided by the Uehara Memorial Foundation, Kanae Foundation for the Promotion of Medical Science, Mochida Memorial Foundation for Medical and Pharmaceutical Research and the Human Frontier Science Program, plus the Medical Scientist Training Program and Pharmacology Training Grant at UC San Diego (T32GM007752)

For instance, MOTS-c is a mitochondrial-derived peptide that also activates AMPK and specifically targets muscle tissue, making it an excellent alternative or cyclic companion to AICAR