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Thus, in addition to the traditionally bipartite communication between the pre- and post-synaptic terminals of neurons, CNS functions depend on a network defined as the tripartite synapse that includes both neurons and astrocytes ([70]

Through various signaling pathwayssuch as neuroendocrine communication, immune modulation, and microbial metabolite productionthe gut microbiota modulates central nervous system function, which subsequently affects cognition, emotion, and behavior

In microfluidic channels samples of blood from high RDW subjects showed flow pattern facilitating direct interaction with vessel wall

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Spontaneous Ca 2+ waves can be propagated to other astrocytes and ultimately cause neuronal activity