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FASEB J 20:E1476E1481 Brown-Borg HM, Rakoczy SG, Romanick MA, Kennedy MA (2002) Effects of growth hormone and insulin-like growth factor-1 on hepatocyte antioxidative enzymes

Cell 162:184197 Levitin HM, Yuan J, Cheng YL, Ruiz FJ, Bush EC, Bruce JN, Canoll P, Iavarone A, Lasorella A, Blei DM et al (2019) De novo gene signature identification from single-cell RNA-seq with hierarchical Poisson factorization

doi: 10.1016/j.freeradbiomed.2015.12.012

Substance- or medication-induced sleep disorder ( DSM-5-TR ) or hypersomnia caused by a drug or substance (ICSD-3-TR) is an important differential diagnosis to suspect when symptoms develop soon after exposure to/withdrawal from a medication/substance with known effects on sleep (Table 2)

In addition to its impressive antioxidant properties, its also said to serve as a physiological buffer that plays a key role in proper enzyme and calcium regulation