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230 A study using the Framingham offspring in the United States found that risk of metabolic syndrome and cardiovascular disease increased significantly, starting at ALT, above the lowest quartile of the normal reference limits

G., Rieckermann, J

As the information from other metabolites was available too (choline and creatine), this information was included for complementary purposes and allows comparability with previous observations (Rodrguez-Nieto et al., 2023)