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J Pharmacol Exp Ther 350:189195

Metformin treatment decreased the abundance of species of Bacteroides fragilis and its bile salt hydrolase activity in the intestines of individuals with T2D, increasing the levels of the bile acid glycoursodeoxycholic acid to inhibit intestinal FXR signaling (47)

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If you want a broader overview of how glutathione fits into wellness, What is Glutathione and Why It Matters for Our Health is a helpful companion read