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Description

AHK-Cu has been studied in relation to hair follicle biology, including its interaction with dermal papilla cells involved in follicle function and cycling

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Briefly, GH binding to preformed dimeric GHR - JAK2 complexes introduces structural changes in the receptor complex that separates JAK2 inhibitory and kinase active sites and enables trans-phosphorylation of the two JAK2 molecules (reviewed in (59)

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