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a total dose of 60 mg/kg/day was well tolerated with no observable adverse effects

Clin Cancer Res 26(14):3525-3536, 2020

AGE can significantly improve the working memory, as well as the reference memory of rats with A-induced cognitive impairment in association with the amelioration of the loss of cholinergic neurons

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With appropriate management, most people can continue their vitamin B12 supplementation whilst maintaining comfortable bowel function