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Therapeutic strategies against antithyroid drugs-induced hepatotoxicity In many cases of antithyroid drugs-induced hepatic injury, no standard and specific treatment is available, except of drug discontinuation and monitoring patients' liver function during hospitalization.27,98 The most performed laboratory tests in antithyroid drugs-induced hepatotoxicity cases, are liver function tests as evaluated by serum aminotransferase levels (AST & ALT) and alkaline phosphatase (ALP) activity.8,99 Other assessments involve serum bilirubin, white blood cells count, prothrombin time (PT), and serum thyroid hormones and TSH levels.99,100 Moreover, abdominal ultrasonography is done to detect any cholestatic changes of patients' liver.6 Drug-induced hepatic injury could be certainly proven when other interacting factors such as viral hepatitis are ruled out

Allowing both the peptide vial and the BAC water to reach room temperature before mixing prevents condensation and helps equalize pressure, making the process smoother and safer for the peptide

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Combination therapy with melphalan is under clinical trials to determine whether BSO can help sensitize resistant neuroblastoma [70]

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