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This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes

[DOI] [PubMed] [Google Scholar] 107.Sacewicz I., Wiktorska M., Wysocki T., Niewiarowska J

Reduces oxidative stress that accelerates follicle aging