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Nelen WL et al

10.1128/CMR.17.4.942-964.2004 150 RosafioK.CastilloX.HirtL.PellerinL

The increased sensitivity of tumor cells as compared to normal cells suggests KPT-330 may be a selective inhibitor with limited off-target toxicity

Dose selection in the research literature varies with the application: musculoskeletal-injury studies commonly report 200250 g twice daily near the affected site, while gastrointestinal-focused protocols use 250500 g once or twice daily, subcutaneously