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Imaging analysis of optical coherence tomography The terminology shallow irregular RPE elevation (SIRE) was recently reported 16 and is a more elaborately defined term of the widely used concept, double-layer sign 17,18,19

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Research applications include: Collagen synthesis and extracellular matrix remodeling Chondrocyte proliferation and differentiation Cartilage repair in osteoarthritis models Joint dysfunction and pain studies In a rabbit model of collagenase-induced knee osteoarthritis, AOD9604 enhanced cartilage regeneration

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