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spinosa may participate in the regulation of ROS production inside and outside the tumor mass in some cancer models, which would confer great antitumor potential (Prieto et al., 2019)

While IGF-I remains the biomarker that best reflects endogenous GH secretion, when there is a discordancy with GH and IGF-I levels, it is important for the clinician to be mindful of the associated changes in intra-portal insulin delivery to the liver when interpreting these results in the context of health and when deciding treatment regimens in disease states

Busch M, Franke S, Ruster C, and Wolf G

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Gottlieb, J