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Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B

CrossRef Occult Hepatitis B Virus Infection in Chronic Hepatitis C Jae Young Jang, Eui Ju Park The Korean Journal of Gastroenterology .2013

IGF-1 LR3 in Stem Cell Self-Renewal Research Research has established that IGF-1 receptor signalling is necessary for human embryonic stem cell self-renewal, and that IGF-1 LR3 can substitute for native IGF-1 in stem cell cultures with increased potency and stability requiring lower concentrations for equivalent or superior biological effects compared to unmodified IGF-1

This is revealing, as abnormalities in circadian rhythms are considered to play a potential underlying role in bipolar disorder, as many genes associated with bipolar disorder including CLOCK , PER3 and BMAL1 are regulated in a circadian manner [70,71,72]