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ANK Deficiency-Mediated Cytosolic Citrate Accumulation Promotes Aortic Aneurysm

RSL3 (MedChemExpress, HY-100218A) was dissolved in 10% DMSO, 40% PEG300, 5% Tween-80 and 45% saline and administered i.p

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In contrast, a randomized clinical trial in women with diminished ovarian reserve used 3 mg/day only during the ART cycle (approximately 35 weeks), reporting higher estradiol levels and improved oocyte and embryo quality without clear effects on pregnancy rates (Jahromi et al., 2017)