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Cannabis-Induced Cytotoxicity in Leukemic Cell Lines: The Role of the Cannabinoid Receptors and the MAPK Pathway

The collective findings reveal that IGF-1 is an essential hormone for normal growth and maintain homeostasis

10.1042/bj1100243 246 HeB.WangK.LiuY.XueB.UverskyV

During the malignant progression of tumors, a variety of signaling pathways are activated to participate in the proliferation, migration, angiogenesis and metabolic remodeling of tumor cells, among which IGFs play important regulatory roles (76)

Because antioxidant enzymes are widely used as biomarkers of marine pollution, research on antioxidant responses to marine environmental changes such as elevated water temperatures is tantamount