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Hines, M

The typical regimen consists of 1 mg (1,000 g) administered three times weekly for two weeks

Severe damage can make the patellar tendon very short, and in such cases, reattachment will be difficult

However, protein misfolding within the ER triggers ER stress, which induces the UPR, a distinct signaling pathway that aims to relieve this stress (Matus et al., 2013