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doi: 10.1016/j.micpath.2019.103599, 82 QingqingB.JieZ.SongbenQ.JuanC.LeiZ.MuX

Gragasin FS, Michelakis ED, Hogan A, Moudgil R, Hashimoto K, Wu X, et al

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This interaction with ACE2 seems to be primed by a proteolytic cleavage of the spike (S) protein by the transmembrane protease serine (TMPRSS2), responsible for the virus interaction with its target receptor (Hoffmann et al., 2020