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In: Targeted Therapy of Acute Myeloid Leukemia, 2015

GR, glucocorticoid receptor

However, there are no hepatitis B vaccines used for therapeutic purposes in clinical practice mainly because most of the recombinant protein vaccines currently under development target HBsAg as a single antigen, which cannot induce a multi-antigen-specific immune response, thus failing to activate low-reactive specific T cells that persist in the subjects bodies