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In cancer cells, erastin, a particular iron apoptosis-inducing chemical, increases heat shock factor 1 (HSF1)-dependent HSPB1 expression

Normal-transit constipation is characterized by normal peristalsis and the absence of any pathological findings, but a persistent perception of being constipated and of inadequate evacuation

doi:10.1016/j.yrtph.2021.104973 Zhao Y, Zhang J, Zheng Y, et al

Nucleic Acid Modifications In the 1990's DNA-based antisense oligodeoxynucleotides (ODN) and ribozymes (RNA) represented an exciting new paradigm for drug design and development, but their application in vivo was prevented by endo- and exo-nuclease activity as well as a lack of successful intracellular delivery

A common feature is immune dysregulation, where, in Graves disease, autoantibodies stimulating the thyroid to produce an excessive amount of hormone and, in Hashimotos thyroiditis, the thyroid gland suffers autoimmune destruction (Bari et al