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Skipping doses or discontinuing treatment prematurely may affect the desired outcomes

61 Canonical and non-canonical signaling pathways involving TGF- often contribute to fibrosis pathogenesis

oral and liposomal forms are also widely available as supplements

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Deficiency is rare in the developed world since meat is widely available and most grains and cereals are fortified with thiamine, but can occur in alcoholics and people who have undergone gastric bypass surgery