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In the current review, we first delineate three cellular defense mechanisms against ferroptosis (GPx4 in the mitochondria and cytosol, FSP1 on plasma membrane, and DHODH in mitochondria), along with four canonical modulators of ferroptosis (system Xc , nuclear factor erythroid 2-related factor 2, p53, and GTP cyclohydrolase-1)

82 However, elevated expression levels of VDAC1 may exert broad chemosensitization effects

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PyNAST: a flexible tool for aligning sequences to a template alignment

Additionally, the study was supplemented with identification of the plasma MDA concentration