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After transient transfection in HEK cells, WT nrf2a strongly activates the transcription of the firefly luciferase reporter gene, whereas both the nrf2a5 and nrf2a fh318 mutants induced much weaker expression of the reporter gene (Fig 1B)

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To better characterize the Nrf2 KOdriven phenotype, we analyzed the expression of thyroid markers on day 7 of our differentiation protocol

Adaptations of Candida albicans for growth in the mammalian intestinal tract