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Therefore, it may lead to better outcomes with fewer side effects

Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats

Under oxidative stress, with the increase in ROS expression, Nrf2 is dissociated from the complex and translocated into the nucleus to bind to the promoter antioxidant response element (ARE) sequence, promoting the expression of Nrf2-related antioxidant enzymes, such as SOD, CAT, heme oxygenase-1 (HO-1), and GPx (Zhang et al., 2021