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SKU: 4677668838
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Prescription & Delivery of Authentic Pens Your pens and vials are prescribed and delivered to your doorstep ensuring 100% authentic, clinical-grade therapy

Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53

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State 3 respiration, shown as the maximal rate of respiration in response to 1 mM ADP, in the presence of either pyruvate-malate, fatty acids, or glutamate-malate was significantly reduced in both DM and DM_CKD groups compared to WT, while State 4 respiration and membrane potential measured by TMRM were unchanged, indicating no relevant mitochondrial uncoupling (Fig